F-actin (green) and nuclear (blue) staining reveals the morphology of the wound edge.
Dye that labels reactive oxygen species (ROS) highlights the new tissues of the blastema in green/red.
Synapsin labeling (green) of the planarian anterior nervous system and brain.
F-actin (green) and nuclear (blue) staining reveals the morphology of the wound edge.
Publications
(** graduate student, * undergraduate student, † contributed equally)
Rishabh, Vučković J**, Zadeh-Haghighi H, Beane WS, & Simon, C. (2024). Verification of radical pair mechanism predictions for weak magnetic field effects on superoxide in Planarians. bioRxiv. https://doi.org/10.1101/2024.11.20.624392. View PDF
Vučković J**, Gurhan H, Gutierrez B**, Guerra J*, Kinsey LJ, Nava I*, Fitzpatrick*, Barnes FS,
Tseng KA-T†, Beane WS†. (2024) Construction and Application of a Static Magnetic Field
Exposure Apparatus for Biological Research in Aqueous Model Systems and Cell Culture. Bioprotocol
Oct 5;14(19): e5077. DOI: 10.21769/BioProtoc.5077. View PDF
Kinsey**, Beane WS†, Tseng KA-S†. (2024) Accelerating an integrative view of quantum biology. Frontiers in Physiology. Section: Quantum-Based Effects on Cell Physiology. 2024 Jan 11;14:1349013. DOI: 10.3389/fphys.2023.1349013. eCollection 2023. View PDF
Witucki A**, Beane WS, Pleasants B, Dai P, Rudge DW. (2023) Redesigning a course based undergraduate research experience for online delivery. Biochemistry and Molecular Biology Education. Nov-Dec;51(6):670-677. DOI: 10.1002/bmb.21780. View PDF
Witucki A**, Beane WS, Pleasants B, Dai P, Rudge DW. (2023) An Explicit and Reflective Approach to Teaching Nature of Science in a Course‑Based Undergraduate Research Experience. Science and Education. https://doi.org/10.1007/s11191-023-00441-8. View PDF
Hack SJ**, Beane WS, Tseng K-AS. (2023) Biophysics at the edge of life and death: Radical control of apoptotic mechanisms. Frontiers in Cell Death. Section:. Apoptosis (Vol 2). 27 February 2023. DOI 10.3389/fceld.2023.1147605. View PDF
Kinsey LJ**, Van Huizen AV**, Beane WS. (2023) Weak magnetic fields modulate superoxide to control planarian regeneration. Frontiers in Physics. Section: Biophysics. 04 January 2023. Vol.10 – 2022. DOI: 10.3389/fphy.2022.1086809. View PDF
Hack SJ**†, Kinsey LJ**†, Beane WS. (2021) An Open Question: Is Non-Ionizing Radiation a Tool for Controlling Apoptosis-Induced Proliferation? International Journal of Molecular Sciences. 2021 Oct 16;22(20):11159. View PDF
Beane WS, Adams DS, Morokuma J, Levin M. (2019) Live imaging of intracellular pH in planarians using the ratiometric fluorescent dye SNARF-5F-AM. Biology Methods and Protocols. 2019;4(1):bpz005. View PDF
Van Huizen AV**, Morton JM*, Kinsey LJ**, Von Kannon DG**, Saad MA*, Birkholz TR**, Czajka JM*, Cyrus J, Barnes FS, Beane WS. (2019) Weak magnetic fields alter stem cell–mediated growth. Science Advances. 5, eaau7201. View PDF
Birkholz TR**, Van Huizen AV**, Beane WS. (2019) Staying in Shape: Planarians as a Model for Understanding Regenerative Morphology. Seminars in Cell and Developmental Biology. Mar;87:105-115. View PDF
Van Huizen AV**, Tseng AS, Beane WS. (2017) Methylisothiazolinone Toxicity and Inhibition of Wound Healing and Regeneration in Planaria. Aquatic Toxicology. Oct;191:226-235. View PDF
Birkholz TR**, Beane WS. (2017) The Planarian TRPA1 Homolog Mediates Extraocular Behavioral Responses to Near Ultraviolet Light. Journal of Experimental Biology. Jul 15;220(Pt 14):2616-2625. View PDF
Morton JM*, Saad MA*, Beane WS. (2017) Surgical Ablation Assay for Studying Eye Regeneration in Planarians. Journal of Visualized Experiments (JoVE). Apr 14;(122). View PDF View Video
Deochand ME**, Birkholz TR**, Beane WS. (2016) Temporal regulation of planarian eye regeneration. Regeneration (Oxf). Oct 28;3(4):209-221. View PDF
Cover: Biology Open. Vol 5(9), Sept 2016.
Cover: Regeneration (Oxf). Vol 3(2), Apr 2016
Schatzberg D, Lawton M, Hadyniak SE, Ross EJ, Carney T, Beane WS, Levin M, Bradham CA. (2015) H+/K+ ATPase activity is required for biomineralization in sea urchin embryos. Developmental Biology. Oct 15;406(2):259-70. View PDF
Paskin TR**, Jellies J, Bacher J*, Beane WS. (2014) Planarian phototactic assay reveals differential behavioral responses based on wavelength. PLoS One. Dec 10;9(12):e114708. View PDF
Beane WS, Morokuma J, Lemire J, Levin M. (2013) Bioelectric signaling regulates head and organ size during planarian regeneration. Development. Jan;140(2):313-322. View PDF
Beane WS, Tseng A, Morokuma J, Lemire J, Levin M. (2012) Inhibition of planar cell polarity extends neural growth during regeneration, homeostasis and development. Stem Cells and Development. Aug 10;21(12):2085-94. View PDF [Cover Image]
Lobo D, Beane WS, Levin M. (2012) Modeling planarian regeneration: a primer for reverse-engineering the worm. PLoS Computational Biology. 8(4) e1002481. View PDF [Featured Image]
Beane WS, Morokuma J, Adams DS, Levin M. (2011) A chemical genetics approach revels H,K-ATPase-mediated membrane voltage is required for planarian head regeneration. Cell Chemical Biology. Jan 28;18(1):77-89. View PDF
Tseng AS, Beane WS, Lemire JM, Masi A, Levin M (2010). Induction of vertebrate regeneration by a transient sodium current. Journal of Neuroscience. Sep 29;30(39): 13192-200. View PDF [Cover Image]
Stevenson CG and Beane WS (2010) A low percent ethanol method for immobilizing planarians. PLoS One. Dec 14;5(12):e15310. View PDF
Oviedo NJ and Beane WS (2009). Regeneration: The origin of cancer or a possible cure? Seminars in Cell and Developmental Biology. Jul;20(5):557-64. View PDF
Bradham CA, Foltz KR, Beane WS, Arnone MI, Rizzo F, Coffman JA, Mushegian A, Goel M, Morales J, Geneviere A-M, Lapraz F, Robertson AJ, Kelkar H, Loza-Coll M, Townley IK, Raisch M, Roux MM, Lapage T, Gache C, McClay DR, Manning G (2006). The sea urchin kinome: a first look. Developmental Biology. Dec 1; 300(1):180-193.
Morales J, Mulner-Lorillon O, Cosson B, Morin E, Bellé R, Bradham CA, Beane WS, Cormier P (2006). Translational control genes in the sea urchin genome. Developmental Biology. Dec 1; 300(1):293-307.
Beane WS, Voronina E, Wessel GM, McClay DR (2006). Lineage-specific expansions provide genomic complexity among sea urchin GTPases. Developmental Biology. Dec 1; 300(1):165-179.
The Sea Urchin Genome Sequencing Consortium (2006). The genome of the sea urchin Strongylocentrotus purpuratus. Science. Nov 10;314(5801):941-952. (My data Fig. 4.)
Beane WS, Gross JM, McClay DR. (2006) RhoA regulates initiation of invagination, but not convergent extension, during sea urchin gastrulation. Developmental Biology. Apr 1; 292(1):213-25.